Fmoc-R-3-Amino-3-(2-methyl-phenyl)-propionic acid is an organic compound that is often used as a protecting group or amino acid in chemical experiments and organic synthesis. Its properties are as follows:
1. Appearance: Colorless or slightly yellow crystalline solid.
2. Molecular formula: C? H? no3.
3. Molecular weight: 334.37g/mol.
4. Melting point: about 100-104°C.
5. Solubility: Soluble in common organic solvents such as dimethyl sulfoxide (DMSO), dichloromethane, dimethylformamide (DMF) and ethanol.
The main use of Fmoc-R-3-Amino-3-(2-methyl-phenyl)-propionic acid is to synthesize peptides, proteins and other drug molecules. It is commonly used as a protecting group for amino acids in polypeptide synthesis and can be removed by acid or base-mediated removal to expose the hydroxyl group of the natural amino acid. It can also be used as an oxalyl reagent to participate in the acylation reaction.
Fmoc-R-3-Amino-3-(2-methyl-phenyl)-propionic acid is usually prepared by chemical synthesis. The specific method is that Fmoc-alanine is reacted with an appropriate acylating agent (such as 2-methylbenzoic anhydride) under reaction conditions to finally obtain the target product.
Regarding safety information, you need to pay attention to the following when using the Fmoc-R-3-Amino-3-(2-methyl-phenyl)-propionic acid:
1. Since Fmoc-R-3-Amino-3-(2-methyl-phenyl)-propionic acid is a chemical agent, contact with skin, eyes or inhalation of its dust should be avoided. Personal protective equipment such as appropriate protective gloves, glasses and protective clothing should be worn during operation.
2. When using, ensure that it is operated in a well-ventilated laboratory environment to avoid inhaling its vapor or dust.
3. Follow laboratory procedures and safety guidelines that meet safety and hygiene requirements.
4. Waste disposal should be carried out in accordance with local regulations to avoid environmental pollution.
Before using Fmoc-R-3-Amino-3-(2-methyl-phenyl)-propionic acid or any other chemical reagent, it is recommended to consult the relevant safety data sheets and technical literature, and follow the laboratory's safety operating guidelines.